Specs at a glance
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Laser wavelength
785 nm -
Sample interface
Temperature: probe is non-contact; operating temp: 10 to 50 °C / 50 to 122 °F
Field of application
The union between our Raman analyzers equipped with Rxn-46 bioprocess probe technology and the BioPAT® Spectro platform by Sartorius offers the market an ideal interface to high-throughput development through single-use commercial manufacturing. Our Raman bioprocessing probe technology has been adapted to fit Sartorius’s BioPAT® Spectro platform, utilizing the same probe design for Ambr® 15, Ambr® 250, & Biostat STR® bioreactors.
Cell culture: glucose, lactate, amino acids, cell density, titer, and more
Benefits
Enables faster, easier, and more robust model building via integration with Ambr® 15 and Ambr® 250
Allows high-throughput process development which supports QbD
Provides a more efficient transfer to Biostat STR® for single-use manufacturing
Offers a scale-independent interface from 15 ml in the laboratory to 2000 L in the production suite
Requires no probe cleaning, sterilization, or frequent maintenance due to non-contact sampling
Extended selection
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High-end products
- Highly functional and convenient
Technical excellence
Simplicity
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Standard products
- Reliable, robust and low-maintenance
Technical excellence
Simplicity
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Specialized products
- Designed for demanding applications
Technical excellence
Simplicity
Variable
| FLEX selections | Technical excellence | Simplicity |
|---|---|---|
Fundamental selection Meet your basic measurement needs |
Technical excellence
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Simplicity
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Lean selection Handle your core processes easily |
Technical excellence
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Simplicity
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Extended selection Optimize your processes with innovative technologies |
Technical excellence
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Simplicity
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Xpert selection Master your most challenging applications |
Technical excellence
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Simplicity
Variable |
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Success stories
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Technical Information (TI)
Raman Rxn-46 calibration and verification kit Technical Information
System design and specifications for the Raman Rxn-46
calibration and verification kitEN 11/01/2024Language:
English
Version:
11/01/2024
File size:
400.4 KB
File name:
TI01765CEN_0123.pdf
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Technical Information (TI)
Rxn-46 Raman spectroscopic probe Technical Information
System design and specifications for the Raman Rxn-46 probe
EN 13/12/2024Language:
English
Version:
13/12/2024
File size:
1 MB
File name:
TI01634CEN_0424.pdf
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Operating Instruction (BA)
Raman Rxn-46 calibration and verification kit Operating Instructions
Commissioning, operation, and maintenance details for the
Raman Rxn-46 calibration and verification kitEN 11/01/2024Language:
English
Version:
11/01/2024
File size:
928.9 KB
File name:
BA02324CEN_0123.pdf
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Operating Instruction (BA)
Rxn-46 Raman spectroscopic probe Operating Instructions
Commissioning, operation, and maintenance details
for the Raman Rxn-46 probeEN 02/12/202411/01/202403/08/202214/09/2021Language:
English
Version:
02/12/2024
File size:
1.3 MB
File name:
BA02170CEN_0424.pdf
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Short Instruction (KA)
Rxn-46 Raman spectroscopic probe Brief Operating Instructions
Quick start guide for the Raman Rxn-46 probe
EN 02/12/202411/01/202403/08/202214/09/2021Language:
English
Version:
02/12/2024
File size:
529 KB
File name:
KA01550CEN_0424.pdf
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PU (Publication)
Biopharma 4.0 model graphic
Graphic illustrating the core elements of Biopharma 4.0 including
product lifecycle stages, role of PAT/QbD, and 12 key advanced
technologies for scientists and process engineers in the Life
Sciences, applicable to Raman spectroscopy systems (Raman
Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and
sleeve, flow cell and flow bench, Raman optic system for single
use, and Raman calibration & verification kits).Language:
English
Version:
22/05/2025
File size:
481.6 KB
File name:
PU01614CEN_0125.pdf
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PU (Publication)
Prioritize scalability for an efficient biopharmaceutical product development lifecycle
This technical paper studies the importance of scalability as a
competitive advantage in bioprocessing in the Life Science industry,
and Endress+Hauser's scalable Raman systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology and Liquid Analysis portfolio
(Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and
Memosens CPS61E, CLS82E, COS81E, CLS82E).Language:
Czech
Version:
06/09/2024
File size:
381.4 KB
File name:
PU01584CEN_0124_cz_view.pdf
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PU (Publication)
Endress+Hauser - ライフサイエンス技術のワンストップパートナー
Endress+Hauserが、ライフサイエンス分野の専門知識と、ラマン分
光システム（Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45、Rxn-46、
バイオマルチオプティックおよびスリーブ、フローフィル、フロー
ベンチ、シングルユース用Ramanオプティックシステム）や水質分
析センサ技術（Liquiline CM44P、CM442、OUSAF44、OUSBT66、
Memosens CPS61E、CLS82E、COS81E、CLS82E）などの信頼性の高い
インラインおよびリアルタイム測定技術によって、世界トップクラ
スのバイオ医薬品メーカーから信頼されている理由を強調したグラ
フィック。Language:
Japanese
Version:
04/10/2024
File size:
2.7 MB
File name:
PU01585CJA_0124_Graphic_EH biopharma trust.pdf
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PU (Publication)
Endress+Hauser - your one-source Life Sciences technology partner
Graphic highlighting why Endress+Hauser is trusted by the
world's top biopharmaceutical manufacturers for its Life
Sciences expertise and reliable inline, real-time measurement
technologies like Raman spectroscopy systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology (Liquiline CM44P, CM442 and
OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E,
CLS82E).Language:
English
Version:
27/06/2024
File size:
1.9 MB
File name:
PU01585CEN_0124.pdf
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PU (Publication)
Kaiser Raman technology and Sartorius BioPAT Spectro® collaboration Q&A - Scalable, real-time bioprocess monitoring solutions
A Q&A about how our Raman spectroscopy analyzer systems
(including the Raman Rxn2 analyzer, Raman Rxn4 analyzer,
and Rxn-46 probe), powered by Kaiser Raman technology, integrates
with the Sartorius BioPAT Spectro platform (Ambr and biostat STR) for
high throughput and single use (SUB) bioprocessingin the
biopharmaceutical life science industry.Language:
English
Version:
08/12/2021
File size:
943.7 KB
File name:
PU01446CEN_0121.pdf
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